Pellets can be a safe and effective method for hormone replacement therapy (HRT) when administered properly. However, as with any medical treatment, there are some risks and considerations to keep in mind.
What are pellets?
- Pellets used for HRT are small implants placed under the skin that release hormones steadily over 3-6 months.
- They contain either estrogen, testosterone, or a combination that is compressed into the size of a grain of rice.
- Once inserted, they release hormones steadily, avoiding the peaks and valleys that can occur with patches, gels, pills or shots.
Benefits of pellets:
- Provide a steady delivery of hormones, avoiding major fluctuations
- Last 3-6 months before needing replacement
- Considered natural and bioidentical since they use estradiol and testosterone
- Single implantation procedure every 3-6 months
- Avoid remembering daily doses
Risks and side effects:
- Infection, bruising or bleeding at the insertion site
- Extrusion - pellets come out through the skin
- Reaction to local anesthetic
- Temporary fluid retention
- Breast swelling and tenderness
- Acne breakouts
- Changes in mood - depression or anxiety
- Headaches
- Unwanted hair growth
- High hematocrit - percentage of blood comprised of red blood cells
Pellet insertion procedure:
- Done in doctor's office with local anesthetic
- Takes 5-10 minutes
- Tiny incision made in hip or abdomen
- Pellets inserted under skin
- Incision closed with tape or sterile glue
Who is a good candidate for pellets?
- Women or men with low hormones confirmed by blood tests
- People who want steady hormone delivery over months
- Those who struggle remembering to take medicines daily
- People not getting symptom relief from other HRT
- Individuals who prefer bioidentical over synthetic hormones
Considerations before getting pellets:
- Use effective birth control - restore fertility
- Have hormones tested to confirm need
- Have any necessary exams like mammogram
- Make sure thyroid is working properly
- Start low dose and adjust as needed
In summary, pellets can provide real benefits when used appropriately under a doctor’s supervision. Getting hormone levels tested, monitoring for side effects, following dosage recommendations, and watching for any reactions at the insertion site is important. For many, pellets offer a convenient way to replace hormones lost with aging or medical conditions. However, the decision should be made carefully with a doctor you trust.
